Hi,
NetXMS has "helpdesk links" - loadable modules that provide interface to ticketing system. If ticketing system supports it, this module can provide two-way integration (as done for Jira). Currently such modules exists only for Jira and RedMine. Unfortunately they are not scripts, but shared libraries written in C++. If you have C++ developers you can build your own link using Jira as example. For 3.0 branch we are considering Python and/or JavaScript extension support, but that's long way ahead anyway. You can also order custom development from our company.
Best regards,
Victor